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Sapala Organics Has Huge Plans in Hyderabad
Sapala Organics have procured about 6.5 acres of land at Keesara for this facility, and in the first phase, they are planning to invest Rs 60 crore
G
Guru Prasad
Hyderabad
Fri Jul 23 2021
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Sapala Organics Has Huge Plans in Hyderabad
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Sapala Organics, a Hyderabad-based company that specializes in custom synthesis, is setting up a state-of-the-art manufacturing facility near Keesara for producing high-value oligonucleotides and compounds to meet additional capacity requirements. According to Dr. PY Reddy, president, and CEO of Sapala Organics, they have procured about 6.5 acres of land at Keesara for this facility, and in the first phase, they are planning to invest Rs 60 crore. In August, the groundbreaking may happen, and it is expected that the plant to be fully commissioned by early 2023. 


The company, which is involved in various activities such as bulk outsourcing, custom synthesis, technical and analytical services, process development, and kilo-scale contract manufacturing, currently operates out of its facility at Phase II, IDA Mallapur in Hyderabad. 


In a major boost to its efforts, along with its Japanese partner, Sapala entered into a supply agreement with a global contract manufacturing organization from the US for the supply of unnatural nucleoside-Pseudouridine (Ψ) N1-Methyl-Pseudouridne (1-Me-Ψ) and cap reagents used in mRNA vaccine development. 


The manufacturing organization uses the N1-Methyl-Pseudouridne to mimic the natural uridine (nucleoside, a subunit of nucleic acids) to impact the coding specificity and to create a mutation to promote suppression of the virus in the human body. In addition, the cap reagents are utilized in the mRNA vaccine development to produce the longest-lasting, most active, and least toxic mRNA.


PY Reddy also mentions that Sapala can synthesize several nucleosides and organic compounds used in therapeutic and diagnostic applications. The company has developed technology for the scale of deoxynucleoside triphosphates (dNTPs) used for the synthesis of probes and primers for diagnostic kits to detect COVID19 and other viruses. The company also developed scale-up technology for lipid nanoparticles such as N-Acetylgalactosamine (GalNAc) compounds used for delivery of the oligonucleotides into the cells.


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Sapala Organics Has Huge Plans in Hyderabad
Sapala Organics Has Huge Plans in Hyderabad
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